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Head of Strain DevelopmentBioTalent • Paris, Île-de-France, France
Head of Strain Development

Head of Strain Development

BioTalent • Paris, Île-de-France, France
Il y a 6 jours
Type de contrat
  • Temps plein
Description de poste

Head of Strain Development

Paris, France | €90,000 - €120,000 + Equity


I'm partnering with a venture-backed industrial biotechnology company developing an AI-enabled bioproduction platform designed to manufacture high-value ingredients using engineered microorganisms. Having successfully moved beyond proof-of-concept science, the business has secured significant funding, established fermentation capabilities, generated patented discoveries and is now scaling towards industrial deployment.


They're looking for a Head of Strain Development to lead the scientific engine behind that ambition. This is an opportunity to take ownership of strain engineering strategy, build a scalable development platform and deliver the production strains that will underpin the company's future success. The company is initially focused on astaxanthin and beta-carotene, with ambitions to build a broader portfolio of industrial ingredients over the coming years. You'll work at the intersection of:

  • Industrial biotechnology
  • Metabolic engineering
  • Protein engineering
  • Synthetic biology
  • Fermentation
  • Platform development


What You'll Be Responsible For

Deliver commercially relevant production strains

  • Develop next-generation astaxanthin production strains
  • Deliver competitive beta-carotene strains
  • Support future ingredient programmes from research through industrialisation readiness


Build a scalable strain development platform

  • Integrate metabolic engineering, protein engineering and screening capabilities
  • Create efficient design-build-test-learn workflows
  • Develop processes capable of supporting a growing ingredient portfolio


Drive strain performance

  • Identify pathway, cofactor, transport, toxicity and regulatory bottlenecks
  • Apply rational design, directed evolution and molecular engineering approaches
  • Translate biological insights into measurable performance improvements


Lead and develop the team

  • Manage and mentor scientists and technicians
  • Establish clear scientific standards and operating procedures
  • Build a culture of accountability, ownership and continuous improvement


Remain scientifically hands-on

  • Design experiments
  • Troubleshoot critical technical challenges
  • Review data and guide scientific decision-making
  • Support high-priority programmes directly when required


What They're Looking For

Technical Experience

  • MSc or PhD in Metabolic Engineering, Synthetic Biology, Biotechnology, Molecular Biology, Microbiology or related discipline
  • 10+ years of relevant experience, including PhD experience
  • Demonstrated success engineering microbial production strains
  • Deep expertise in metabolic engineering
  • Strong protein engineering knowledge, including directed evolution and rational design
  • Strong molecular biology background, including construct design, cloning and transformation
  • Experience designing or operating screening platforms
  • Strong experimental design and data-analysis capability
  • Experience working with industrial IP and commercially relevant technologies


Leadership Experience

  • Experience managing scientists and technicians
  • Ability to develop strain engineering strategy from first principles
  • Strong decision-making and prioritisation skills
  • Commercial awareness and understanding of scale-up challenges
  • Clear communication and leadership capability


Package

  • €90,000 - €120,000 base salary
  • Significant equity participation
  • Health insurance for you and your family
  • Transport allowance
  • Lunch vouchers
  • Team events and lunches


If you've successfully engineered microbial production strains and are excited by the opportunity to build a world-class strain development platform, I'd be keen to speak confidentially.

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Head of Strain Development • Paris, Île-de-France, France

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